Depletion of HDAC6 Enhances Cisplatin-Induced DNA Damage and Apoptosis in Non-Small Cell Lung Cancer Cells

Depletion of HDAC6 Enhances Cisplatin-Induced DNA Damage and Apoptosis in Non-Small Cell Lung Cancer Cells

Histone deacetylase inhibitors (HDACi) are promising therapeutic agents which are currently used in combination with chemotherapeutic agents in clinical trials for cancer treatment including non-small cell lung cancer (NSCLC). However, the mechanisms underlying their anti-tumor activities remain elu...

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Bibliographic Details
Main Authors: Wang, Lei, Xiang, Shengyan, Williams, Kendra A., Dong, Huiqin, Bai, Wenlong, Nicosia, Santo V., Khochbin, Saadi, Bepler, Gerold, Zhang, Xiaohong
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434198/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434198/

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