Prevention of vaginal SHIV transmission in macaques by a live recombinant Lactobacillus

Most HIV transmission in women occurs through the cervicovaginal mucosa, which is coated by a bacterial biofilm including Lactobacillus. This commensal bacterium plays a role in maintaining healthy mucosa and can be genetically engineered to produce anti-viral peptides. Here, we report a 63% reducti...

Full description

Bibliographic Details
Main Authors: Lagenaur, Laurel A, Sanders-Beer, Brigitte E, Brichacek, Beda, Pal, Ranajit, Liu, Xiaowen, Liu, Yang, Yu, Rosa, Venzon, David, Lee, Peter P, Hamer, Dean H
Format: Online
Language:English
Published: 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3433722/