CD26 expression and adenosine deaminase activity in regulatory T cells (Treg) and CD4+ T effector cells in patients with head and neck squamous cell carcinoma

Adenosine deaminase (ADA) is responsible for the deamination of immunosuppressive adenosine to inosine. In human T lymphocytes, ADA is associated with dipeptidyl peptidase IV (CD26). ADA expression and activity were evaluated in regulatory T cells (Treg) and CD4+ T effector cells (Teff) of patients...

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Main Authors: Mandapathil, Magis, Szczepanski, Miroslaw, Harasymczuk, Malgorzata, Ren, Jin, Cheng, Dongmei, Jackson, Edwin K., Gorelik, Elieser, Johnson, Jonas, Lang, Stephan, Whiteside, Theresa L
Format: Online
Language:English
Published: Landes Bioscience 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429570/