Hepatitis C Virus Translation Preferentially Depends on Active RNA Replication

Hepatitis C virus (HCV) RNA initiates its replication on a detergent-resistant membrane structure derived from the endoplasmic reticulum (ER) in the HCV replicon cells. By performing a pulse-chase study of BrU-labeled HCV RNA, we found that the newly-synthesized HCV RNA traveled along the anterograd...

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Bibliographic Details
Main Authors: Liu, Helene Minyi, Aizaki, Hideki, Machida, Keigo, Ou, J.-H. James, Lai, Michael M. C.
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3427374/

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