Zebrafish foxP2 Zinc Finger Nuclease Mutant Has Normal Axon Pathfinding

foxP2, a forkhead-domain transcription factor, is critical for speech and language development in humans, but its role in the establishment of CNS connectivity is unclear. While in vitro studies have identified axon guidance molecules as targets of foxP2 regulation, and cell culture assays suggest...

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Bibliographic Details
Main Authors: Xing, Lingyan, Hoshijima, Kazuyuki, Grunwald, David J., Fujimoto, Esther, Quist, Tyler S., Sneddon, Jacob, Chien, Chi-Bin, Stevenson, Tamara J., Bonkowsky, Joshua L.
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3427223/