Alterations of the TP53 Gene in Gastric and Esophageal Carcinogenesis

TP53 genes is one of more important tumor suppressor gene, which acts as a potent transcription factor with fundamental role in the maintenance of genetic stability. The development of esophageal and gastric cancers is a multistep process resulting in successive accumulation of genetic alterations...

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Bibliographic Details
Main Authors: Bellini, Marilanda Ferreira, Cadamuro, Aline Cristina Targa, Succi, Maysa, Proença, Marcela Alcântara, Silva, Ana Elizabete
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3420349/