Development of an MRI-visible nonviral vector for siRNA delivery targeting gastric cancer

Development of an MRI-visible nonviral vector for siRNA delivery targeting gastric cancer

An antibody-directed nonviral vector, polyethylene glycol-grafted polyethylenimine functionalized with superparamagnetic iron oxide nanoparticles and a gastric cancer-associated CD44v6 single-chain variable fragment (scFvCD44v6,-PEG-g-PEI-SPION), was constructed as a gastric cancer-targeting and mag...

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Bibliographic Details
Main Authors: Chen, Yinting, Wang, Weiwei, Lian, Guoda, Qian, Chenchen, Wang, Lingyun, Zeng, Linjuan, Liao, Chengde, Liang, Biling, Huang, Bing, Huang, Kaihong, Shuai, Xintao
Format: Online
Language:English
Published: Dove Medical Press 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3405872/

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