Research progress on siRNA delivery with nonviral carriers

RNA interference is a powerful method for the knockdown of pathologically relevant genes. Small interfering RNAs (siRNAs) have been widely demonstrated as effective biomedical genetic-therapy applications for many diseases. Unfortunately, siRNA duplexes are not ideal drug-like molecules. Problems hi...

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Bibliographic Details
Main Authors: Gao, Yan, Liu, Xin-Ling, Li, Xiao-Rong
Format: Online
Language:English
Published: Dove Medical Press 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3124387/