Research progress on siRNA delivery with nonviral carriers
RNA interference is a powerful method for the knockdown of pathologically relevant genes. Small interfering RNAs (siRNAs) have been widely demonstrated as effective biomedical genetic-therapy applications for many diseases. Unfortunately, siRNA duplexes are not ideal drug-like molecules. Problems hi...
Main Authors: | , , |
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Format: | Online |
Language: | English |
Published: |
Dove Medical Press
2011
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3124387/ |