Activation of the cGMP/Protein Kinase G Pathway by Nitric Oxide Can Decrease TRPV1 Activity in Cultured Rat Dorsal Root Ganglion Neurons

Activation of the cGMP/Protein Kinase G Pathway by Nitric Oxide Can Decrease TRPV1 Activity in Cultured Rat Dorsal Root Ganglion Neurons

Recent studies have demonstrated that nitric oxide (NO) activates transient receptor potential vanilloid subtype 1 (TRPV1) via S-nitrosylation of the channel protein. NO also modulates various cellular functions via activation of the soluble guanylyl cyclase (sGC)/protein kinase G (PKG) pathway and...

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Bibliographic Details
Main Authors: Jin, Yunju, Kim, Jun, Kwak, Jiyeon
Format: Online
Language:English
Published: The Korean Physiological Society and The Korean Society of Pharmacology 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3394925/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3394925/

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