Capsaicin Blocks the Hyperpolarization-Activated Inward Currents via TRPV1 in the Rat Dorsal Root Ganglion Neurons

Capsaicin, the pungent ingredient in hot pepper, activates nociceptors to produce pain and inflammation. However, prolonged exposures of capsaicin will cause desensitization to nociceptive stimuli. Hyperpolarization-activated cation currents (Ih) contribute to the maintenance of the resting membrane...

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Bibliographic Details
Main Author: Kwak, Jiyeon
Format: Online
Language:English
Published: The Korean Society for Brain and Neural Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3381215/