The Role of LEF1 in Endometrial Gland Formation and Carcinogenesis

The Role of LEF1 in Endometrial Gland Formation and Carcinogenesis

Endometrial carcinoma is the most common gynecologic cancer, yet the mechanisms underlying this disease process are poorly understood. We hypothesized that Lef1 is required for endometrial gland formation within the uterus and is overexpressed in endometrial cancer. Using Lef1 knockout (KO) mice, we...

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Bibliographic Details
Main Authors: Shelton, Dawne N., Fornalik, Hubert, Neff, Traci, Park, Soo Yeun, Bender, David, DeGeest, Koen, Liu, Xiaoming, Xie, Weiliang, Meyerholz, David K., Engelhardt, John F., Goodheart, Michael J.
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3391280/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3391280/

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