Hypoxia and Angiogenesis in Endometrioid Endometrial Carcinogenesis

Background: Hypoxia-inducible factor 1α (HIF-1α) plays an essential role in the adaptive response of cells to hypoxia, triggering biologic events associated with aggressive tumor behavior. Methods: Expression of HIF-1α and proteins in the HIF-1α pathway (Glut-1, CAIX, VEGF) in paraffin-embedded spe...

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Bibliographic Details
Main Authors: Horrée, Nicole, van Diest, Paul J., van der Groep, Petra, Sie-Go, Daisy M. D. S., Heintz, A. Peter M.
Format: Online
Language:English
Published: IOS Press 2007
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618415/