Once again on rapamycin-induced insulin resistance and longevity: despite of or owing to
Calorie restriction (CR), which deactivates the nutrient-sensing mTOR pathway, slows down aging and prevents age-related diseases such as type II diabetes. Compared with CR, rapamycin more efficiently inhibits mTOR. Noteworthy, severe CR and starvation cause a reversible condition known as “starvati...
| Main Author: | |
|---|---|
| Format: | Online |
| Language: | English |
| Published: |
Impact Journals LLC
2012
|
| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384435/ |