Accurate extension of multiple sequence alignments using a phylogeny-aware graph algorithm
Motivation: Accurate alignment of large numbers of sequences is demanding and the computational burden is further increased by downstream analyses depending on these alignments. With the abundance of sequence data, an integrative approach of adding new sequences to existing alignments without their...
Main Authors: | , , |
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Format: | Online |
Language: | English |
Published: |
Oxford University Press
2012
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3381962/ |