Ultra-large alignments using phylogeny-aware profiles

Many biological questions, including the estimation of deep evolutionary histories and the detection of remote homology between protein sequences, rely upon multiple sequence alignments and phylogenetic trees of large datasets. However, accurate large-scale multiple sequence alignment is very diffic...

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Bibliographic Details
Main Authors: Nguyen, Nam-phuong D., Mirarab, Siavash, Kumar, Keerthana, Warnow, Tandy
Format: Online
Language:English
Published: BioMed Central 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4492008/