One remarkable molecule: Filaggrin
The discovery, in 2006, that loss-of-function mutations in the filaggrin gene (FLG) are the cause of ichthyosis vulgaris – the most common disorder of keratinization – and also a strong genetic risk factor for atopic eczema, marked a significant breakthrough in the understanding of eczema pathogenes...
| Main Authors: | , |
|---|---|
| Format: | Online |
| Language: | English |
| Published: |
2011
|
| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3378480/ |