A genome-wide association meta-analysis identifies new childhood obesity loci

Multiple genetic variants have been associated with adult obesity and a few with severe obesity in childhood; however, less progress has been made to establish genetic influences on common early-onset obesity. We performed a North American-Australian-European collaborative meta-analysis of fourteen...

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Main Authors: Bradfield, Jonathan P., Taal, H. Rob, Timpson, Nicholas J., Scherag, André, Lecoeur, Cecile, Warrington, Nicole M., Hypponen, Elina, Holst, Claus, Valcarcel, Beatriz, Thiering, Elisabeth, Salem, Rany M., Schumacher, Fredrick R., Cousminer, Diana L., Sleiman, Patrick M.A., Zhao, Jianhua, Berkowitz, Robert I., Vimaleswaran, Karani S., Jarick, Ivonne, Pennell, Craig E., Evans, David M., St. Pourcain, Beate, Berry, Diane J., Mook-Kanamori, Dennis O, Hofman, Albert, Rivadeinera, Fernando, Uitterlinden, André G., van Duijn, Cornelia M., van der Valk, Ralf J.P., de Jongste, Johan C., Postma, Dirkje S., Boomsma, Dorret I., Gauderman, William J., Hassanein, Mohamed T., Lindgren, Cecilia M., Mägi, Reedik, Boreham, Colin A.G., Neville, Charlotte E., Moreno, Luis A., Elliott, Paul, Pouta, Anneli, Hartikainen, Anna-Liisa, Li, Mingyao, Raitakari, Olli, Lehtimäki, Terho, Eriksson, Johan G., Palotie, Aarno, Dallongeville, Jean, Das, Shikta, Deloukas, Panos, McMahon, George, Ring, Susan M., Kemp, John P., Buxton, Jessica L., Blakemore, Alexandra I.F., Bustamante, Mariona, Guxens, Mònica, Hirschhorn, Joel N., Gillman, Matthew W., Kreiner-Møller, Eskil, Bisgaard, Hans, Gilliland, Frank D., Heinrich, Joachim, Wheeler, Eleanor, Barroso, Inês, O'Rahilly, Stephen, Meirhaeghe, Aline, Sørensen, Thorkild I.A., Power, Chris, Palmer, Lyle J., Hinney, Anke, Widen, Elisabeth, Farooqi, I. Sadaf, McCarthy, Mark I., Froguel, Philippe, Meyre, David, Hebebrand, Johannes, Jarvelin, Marjo-Riitta, Jaddoe, Vincent W.V., Smith, George Davey, Hakonarson, Hakon, Grant, Struan F.A.
Format: Online
Language:English
Published: 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3370100/