Aflatoxin-Induced TP53 R249S Mutation in HepatoCellular Carcinoma in Thailand: Association with Tumors Developing in the Absence of Liver Cirrhosis

Primary Liver Cancer (PLC) is the leading cause of death by cancer among males in Thailand and the 3rd among females. Most cases are hepatocellular carcinoma (HCC) but cholangiocarcinomas represent between 4 and 80% of liver cancers depending upon geographic area. Most HCC are associated with chroni...

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Main Authors: Villar, Stephanie, Ortiz-Cuaran, Sandra, Abedi-Ardekani, Behnoush, Gouas, Doriane, Nogueira da Costa, Andre, Plymoth, Amelie, Khuhaprema, Thiravud, Kalalak, Anant, Sangrajrang, Suleeporn, Friesen, Marlin D., Groopman, John D., Hainaut, Pierre
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3366967/