Seasonal Variation in TP53 R249S-Mutated Serum DNA with Aflatoxin Exposure and Hepatitis B Virus Infection

Background: Chronic hepatitis B virus (HBV) infection and dietary aflatoxin B1 (AFB1) exposure are etiological factors for hepatocellular carcinoma (HCC) in countries with hot, humid climates. HCC often harbors a TP53 (tumor protein p53) mutation at codon 249 (R249S). In chronic carriers, 1762T/1764...

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Main Authors: Villar, Stéphanie, Le Roux-Goglin, Emilie, Gouas, Doriane A., Plymoth, Amelie, Ferro, Gilles, Boniol, Mathieu, Lereau, Myriam, Bah, Ebrima, Hall, Andrew J., Wild, Christopher P., Mendy, Maimuna, Norder, Helene, van der Sande, Marianne, Whittle, Hilton, Friesen, Marlin D., Groopman, John D., Hainaut, Pierre
Format: Online
Language:English
Published: National Institute of Environmental Health Sciences 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3226502/