Supernatants from culture of type I collagen-stimulated PBMC from patients with cutaneous systemic sclerosis versus localized scleroderma demonstrate suppression of MMP-1 by fibroblasts
Systemic sclerosis (SSc) is a chronic fibrosing disease characterized by vasculopathy, autoimmunity, and an accumulation of collagen in tissues. Numerous studies have shown that compared to healthy or diseased controls, the peripheral blood mononuclear cells (PBMC) from patients with SSc produce a v...
| Main Authors: | , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Springer-Verlag
2012
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3362697/ |