Donor Age of Human Platelet Lysate Affects Proliferation and Differentiation of Mesenchymal Stem Cells

The regenerative potential declines upon aging. This might be due to cell-intrinsic changes in stem and progenitor cells or to influences by the microenvironment. Mesenchymal stem cells (MSC) raise high hopes in regenerative medicine. They are usually culture expanded in media with fetal calf serum...

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Bibliographic Details
Main Authors: Lohmann, Michael, Walenda, Gudrun, Hemeda, Hatim, Joussen, Sylvia, Drescher, Wolf, Jockenhoevel, Stefan, Hutschenreuter, Gabriele, Zenke, Martin, Wagner, Wolfgang
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3360602/