Inhibition of autophagy impairs tumor cell invasion in an organotypic model

Autophagy is a membrane-trafficking process that delivers cytoplasmic constituents to lysosomes for degradation. It contributes to energy and organelle homeostasis and the preservation of proteome and genome integrity. Although a role in cancer is unquestionable, there are conflicting reports that a...

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Bibliographic Details
Main Authors: Macintosh, Robin L., Timpson, Paul, Thorburn, Jacqueline, Anderson, Kurt I., Thorburn, Andrew, Ryan, Kevin M.
Format: Online
Language:English
Published: Landes Bioscience 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3359125/