The Core Apoptotic Executioner Proteins CED-3 and CED-4 Promote Initiation of Neuronal Regeneration in Caenorhabditis elegans

The Core Apoptotic Executioner Proteins CED-3 and CED-4 Promote Initiation of Neuronal Regeneration in Caenorhabditis elegans

Laser severing of individual axons in the nematode Caenorhabditis elegans revealed that the apoptotic executioner caspase CED-3 and its regulator CED-4/Apaf-1 play an unexpected beneficial role in promoting axonal regeneration.

Bibliographic Details
Main Authors: Pinan-Lucarre, Berangere, Gabel, Christopher V., Reina, Christopher P., Hulme, S. Elizabeth, Shevkoplyas, Sergey S., Slone, R. Daniel, Xue, Jian, Qiao, Yujie, Weisberg, Sarah, Roodhouse, Kevin, Sun, Lin, Whitesides, George M., Samuel, Aravinthan, Driscoll, Monica
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3358320/

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