TRIM16 Acts as an E3 Ubiquitin Ligase and Can Heterodimerize with Other TRIM Family Members

The TRIM family of proteins is distinguished by its tripartite motif (TRIM). Typically, TRIM proteins contain a RING finger domain, one or two B-box domains, a coiled-coil domain and the more variable C-terminal domains. TRIM16 does not have a RING domain but does harbour two B-box domains. Here we...

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Bibliographic Details
Main Authors: Bell, Jessica L., Malyukova, Alena, Holien, Jessica K., Koach, Jessica, Parker, Michael W., Kavallaris, Maria, Marshall, Glenn M., Cheung, Belamy B.
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3357404/