ERRATUM: Bapineuzumab captures the N-terminus of the Alzheimer's disease amyloid-beta peptide in a helical conformation

by Miles, Luke A., Crespi, Gabriela A. N., Doughty, Larissa, Parker, Michael W.
Published 2013

Bapineuzumab captures the N-terminus of the Alzheimer's disease amyloid-beta peptide in a helical conformation

by Miles, Luke A., Crespi, Gabriela A. N., Doughty, Larissa, Parker, Michael W.
Published 2013

Potent hepatitis C inhibitors bind directly to NS5A and reduce its affinity for RNA

by Ascher, David B., Wielens, Jerome, Nero, Tracy L., Doughty, Larissa, Morton, Craig J., Parker, Michael W.
Published 2014

Molecular basis for mid-region amyloid-β capture by leading Alzheimer's disease immunotherapies

by Crespi, Gabriela A. N., Hermans, Stefan J., Parker, Michael W., Miles, Luke A.
Published 2015

Activity-Modulating Monoclonal Antibodies to the Human Serine Protease HtrA3 Provide Novel Insights into Regulating HtrA Proteolytic Activities

by Singh, Harmeet, Nero, Tracy L., Wang, Yao, Parker, Michael W., Nie, Guiying
Published 2014

TRIM16 Acts as an E3 Ubiquitin Ligase and Can Heterodimerize with Other TRIM Family Members

by Bell, Jessica L., Malyukova, Alena, Holien, Jessica K., Koach, Jessica, Parker, Michael W., Kavallaris, Maria, Marshall, Glenn M., Cheung, Belamy B.
Published 2012

Direct involvement of the TEN domain at the active site of human telomerase

by Jurczyluk, Julie, Nouwens, Amanda S., Holien, Jessica K., Adams, Timothy E., Lovrecz, George O., Parker, Michael W., Cohen, Scott B., Bryan, Tracy M.
Published 2011

Manipulating the Lewis antigen specificity of the cholesterol-dependent cytolysin lectinolysin

by Lawrence, Sara L., Feil, Susanne C., Holien, Jessica K., Kuiper, Michael J., Doughty, Larissa, Dolezal, Olan, Mulhern, Terrence D., Tweten, Rodney K., Parker, Michael W.
Published 2012

Small Molecule Proprotein Convertase Inhibitors for Inhibition of Embryo Implantation

by Ho, Huiting, Singh, Harmeet, Heng, Sophea, Nero, Tracy L., Paule, Sarah, Parker, Michael W., Johnson, Alan T., Jiao, Guan-Sheng, Nie, Guiying
Published 2013

Unexpected mechanisms of action for a cytokine receptor-blocking antibody

by Hercus, Timothy R, Broughton, Sophie E, Hardy, Matthew P, Nero, Tracy L, Wilson, Nicholas J, Parker, Michael W, Lopez, Angel F
Published 2014

Crystal structure of Streptococcus pneumoniae pneumolysin provides key insights into early steps of pore formation

by Lawrence, Sara L., Feil, Susanne C., Morton, Craig J., Farrand, Allison J., Mulhern, Terrence D., Gorman, Michael A., Wade, Kristin R., Tweten, Rodney K., Parker, Michael W.
Published 2015

Mechanistic Scrutiny Identifies a Kinetic Role for Cytochrome b5 Regulation of Human Cytochrome P450c17 (CYP17A1, P450 17A1)

by Simonov, Alexandr N., Holien, Jessica K., Yeung, Joyee Chun In, Nguyen, Ann D., Corbin, C. Jo, Zheng, Jie, Kuznetsov, Vladimir L., Auchus, Richard J., Conley, Alan J., Bond, Alan M., Parker, Michael W., Rodgers, Raymond J., Martin, Lisandra L.
Published 2015

Structural basis of allosteric and synergistic activation of AMPK by furan-2-phosphonic derivative C2 binding

by Langendorf, Christopher G., Ngoei, Kevin R. W., Scott, John W., Ling, Naomi X. Y., Issa, Sam M. A., Gorman, Michael A., Parker, Michael W., Sakamoto, Kei, Oakhill, Jonathan S., Kemp, Bruce E.
Published 2016

From Knock-Out Phenotype to Three-Dimensional Structure of a Promising Antibiotic Target from Streptococcus pneumoniae

by Dogovski, Con, Gorman, Michael A., Ketaren, Natalia E., Praszkier, Judy, Zammit, Leanne M., Mertens, Haydyn D., Bryant, Gary, Yang, Ji, Griffin, Michael D. W., Pearce, F. Grant, Gerrard, Juliet A., Jameson, Geoffrey B., Parker, Michael W., Robins-Browne, Roy M., Perugini, Matthew A.
Published 2013

CSL311, a novel, potent, therapeutic monoclonal antibody for the treatment of diseases mediated by the common β chain of the IL-3, GM-CSF and IL-5 receptors

by Panousis, Con, Dhagat, Urmi, Edwards, Kirsten M., Rayzman, Veronika, Hardy, Matthew P., Braley, Hal, Gauvreau, Gail M., Hercus, Timothy R., Smith, Steven, Sehmi, Roma, McMillan, Laura, Dottore, Mara, McClure, Barbara J., Fabri, Louis J., Vairo, Gino, Lopez, Angel F, Parker, Michael W., Nash, Andrew D., Wilson, Nicholas J., Wilson, Michael J., Owczarek, Catherine M.
Published 2015

Phosphorothioate backbone modifications of nucleotide-based drugs are potent platelet activators

by Flierl, Ulrike, Nero, Tracy L., Lim, Bock, Arthur, Jane F., Yao, Yu, Jung, Stephanie M., Gitz, Eelo, Pollitt, Alice Y., Zaldivia, Maria T.K., Jandrot-Perrus, Martine, Schäfer, Andreas, Nieswandt, Bernhard, Andrews, Robert K., Parker, Michael W., Gardiner, Elizabeth E., Peter, Karlheinz
Published 2015