Intake levels of dietary long-chain PUFAs modify the association between genetic variation in FADS and LDL-C[S]

Polymorphisms of the FA desaturase (FADS) gene cluster have been associated with LDL, HDL, and triglyceride concentrations. Because FADS converts α-linolenic acid (ALA) and linoleic acid into PUFAs, we investigated the interaction between different PUFA intakes and the FADS polymorphism rs174547 (T&...

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Bibliographic Details
Main Authors: Hellstrand, S., Sonestedt, E., Ericson, U., Gullberg, B., Wirfält, E., Hedblad, B., Orho-Melander, M.
Format: Online
Language:English
Published: The American Society for Biochemistry and Molecular Biology 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351825/