Nitazoxanide Stimulates Autophagy and Inhibits mTORC1 Signaling and Intracellular Proliferation of Mycobacterium tuberculosis

Nitazoxanide Stimulates Autophagy and Inhibits mTORC1 Signaling and Intracellular Proliferation of Mycobacterium tuberculosis

Tuberculosis, caused by Mycobacterium tuberculosis infection, is a major cause of morbidity and mortality in the world today. M. tuberculosis hijacks the phagosome-lysosome trafficking pathway to escape clearance from infected macrophages. There is increasing evidence that manipulation of autophagy,...

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Bibliographic Details
Main Authors: Lam, Karen K. Y., Zheng, Xingji, Forestieri, Roberto, Balgi, Aruna D., Nodwell, Matt, Vollett, Sarah, Anderson, Hilary J., Andersen, Raymond J., Av-Gay, Yossef, Roberge, Michel
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349752/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349752/

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