Amino Acid Sensing by mTORC1: Intracellular Transporters Mark the Spot
Cell metabolism and growth are matched to nutrient availability via the amino-acid-regulated mechanistic target of rapamycin complex 1 (mTORC1). Transporters have emerged as important amino acid sensors controlling mTOR recruitment and activation at the surface of multiple intracellular compartments...
| Main Authors: | , , |
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| Format: | Online |
| Language: | English |
| Published: |
Cell Press
2016
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5067300/ |