Triggering of Toll-like Receptor-2 in Mouse Myelomonocytic Leukaemia Cells WEHI-3B Leads to the Suppression of Apoptosis and Promotes Tumor Progression in Vivo

Toll-like receptors are the essential components of innate immunity. It is shown that TLRs play an essential role in the immune resistance of an organism to bacterial and viral infections. The binding of TLR to its own ligands results in the activation of several adapter molecules and kinases, induc...

Full description

Bibliographic Details
Main Authors: Shcheblyakov, D.V., Logunov, D.Y., Rakovskaya, I.V., Shmarov, M.M., Naroditsky, B.S., Ginzburg, A.L.
Format: Online
Language:English
Published: A.I. Gordeyev 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3347616/