An Efficient Method for the Delivery of the Interleukin-2 Gene to Human Hematopoietic Cells using the Fiber-Modified Recombinant Adenovirus
Recombinant human adenovirus serotype 5 (Ad5/35F-IL2) with modified fibres containing the C-terminal domain fiber-knob of human adenovirus serotype 35, carrying the gene of recombinant human IL-2, has been designed. As a result of the fiber modification, the adenovirus can efficiently deliver the ge...
Main Authors: | , , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
A.I. Gordeyev
2011
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3347609/ |