Oxaliplatin-induced neurotoxicity involves TRPM8 in the mechanism of acute hypersensitivity to cold sensation
Oxaliplatin-induced peripheral neurotoxicity (OPN) is commonly associated with peripheral hypersensitivity to cold sensations (CS) but the mechanism is unknown. We hypothesized that the transient receptor potential melastatin 8 (TRPM8), a putative cold and menthol receptor, contributes to oxaliplati...
| Main Authors: | , , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Blackwell Publishing Inc
2012
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3343300/ |