Tying the knot: The cystine signature and molecular-recognition processes of the vascular endothelial growth factor family of angiogenic cytokines
The cystine-knot motif, made up of three intertwined disulfide bridges, is a unique feature of several toxins, cyclotides and growth factors, and occurs in a variety of species, including fungi, insects, molluscs and mammals. Growth factor molecules containing the cystine-knot motif serve as ligands...
Main Authors: | , |
---|---|
Format: | Online |
Language: | English |
Published: |
Blackwell Publishing Ltd
2011
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3328748/ |