Functional evolution of scorpion venom peptides with an inhibitor cystine knot fold
The ICK (inhibitor cystine knot) defines a large superfamily of polypeptides with high structural stability and functional diversity. Here, we describe a new scorpion venom-derived K+ channel toxin (named λ-MeuKTx-1) with an ICK fold through gene cloning, chemical synthesis, nuclear magnetic resonan...
| Main Authors: | , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Portland Press Ltd.
2013
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694633/ |