The ATPase activity of MLH1 is required to orchestrate DNA double-strand breaks and end processing during class switch recombination

MLH1 ATPase activity is essential for class switch recombination but not for somatic hypermutation.

Bibliographic Details
Main Authors: Chahwan, Richard, van Oers, Johanna M.M., Avdievich, Elena, Zhao, Chunfang, Edelmann, Winfried, Scharff, Matthew D., Roa, Sergio
Format: Online
Language:English
Published: The Rockefeller University Press 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3328365/