An inactivating caspase 11 passenger mutation originating from the 129 murine strain in mice targeted for c-IAP1

An inactivating caspase 11 passenger mutation originating from the 129 murine strain in mice targeted for c-IAP1

A recent study revealed that ES (embryonic stem) cell lines derived from the 129 murine strain carry an inactivating mutation within the caspase 11 gene (Casp4) locus [Kayagaki, Warming, Lamkanfi, Vande Walle, Louie, Dong, Newton, Qu, Liu, Heldens, Zhang, Lee, Roose-Girma and Dixit (2011) Nature 479...

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Bibliographic Details
Main Authors: Kenneth, Niall S., Younger, J. Michael, Hughes, Elizabeth D., Marcotte, Danielle, Barker, Philip A., Saunders, Thomas L., Duckett, Colin S.
Format: Online
Language:English
Published: Portland Press Ltd. 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3327503/

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