Pneumococcal Conjugate and Plain Polysaccharide Vaccines Have Divergent Effects on Antigen-Specific B Cells

Pneumococcal Conjugate and Plain Polysaccharide Vaccines Have Divergent Effects on Antigen-Specific B Cells

Background. A 23-valent unconjugated pneumococcal polysaccharide vaccine (23vP), routinely administered at the age of 65, has limited effectiveness, and revaccination induces attenuated antibody responses. It is not known whether pneumococcal polysaccharide-protein conjugated vaccines (PCV), althoug...

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Bibliographic Details
Main Authors:	Clutterbuck, Elizabeth A., Lazarus, Rajeka, Yu, Ly-Mee, Bowman, Jaclyn, Bateman, Elizabeth A. L., Diggle, Linda, Angus, Brian, Peto, Tim E., Beverley, Peter C., Mant, David, Pollard, Andrew J.
Format:	Online
Language:	English
Published:	Oxford University Press 2012
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3324398/

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