Targeting colorectal cancer stem cells with inducible caspase-9

Targeting colorectal cancer stem cells with inducible caspase-9

Colorectal cancer stem cells (CSCs) drive tumor growth and are suggested to initiate distant metastases. Moreover, colon CSCs are reportedly more resistant to conventional chemotherapy, which is in part due to upregulation of anti-apoptotic Bcl-2 family members. To determine whether we could circumv...

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Bibliographic Details
Main Authors:	Kemper, Kristel, Rodermond, Hans, Colak, Selçuk, Grandela, Catarina, Medema, Jan Paul
Format:	Online
Language:	English
Published:	Springer US 2012
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3322325/

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