Targeting colorectal cancer stem cells with inducible caspase-9
Colorectal cancer stem cells (CSCs) drive tumor growth and are suggested to initiate distant metastases. Moreover, colon CSCs are reportedly more resistant to conventional chemotherapy, which is in part due to upregulation of anti-apoptotic Bcl-2 family members. To determine whether we could circumv...
| Main Authors: | , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Springer US
2012
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3322325/ |