A Molecular Model for the Differential Activation of STAT3 and STAT6 by the Herpesviral Oncoprotein Tip

A Molecular Model for the Differential Activation of STAT3 and STAT6 by the Herpesviral Oncoprotein Tip

Constitutive STAT signaling provides growth promoting signals in many forms of malignancy. We performed molecular modeling and molecular dynamics studies of the interaction between the regulatory Src homology 2 (SH2) domains of STAT3 and 6 with phosphorylated peptides of the herpesviral oncoprotein...

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Bibliographic Details
Main Authors: Mazumder, Eman Dey, Jardin, Christophe, Vogel, Benjamin, Heck, Elke, Scholz, Brigitte, Lengenfelder, Doris, Sticht, Heinrich, Ensser, Armin
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3320567/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3320567/

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