Transcriptional regulation by STAT1 and STAT2 in the interferon JAK-STAT pathway
STAT1 and STAT2 proteins are key mediators of type I and type III interferon (IFN) signaling, and are essential components of the cellular antiviral response and adaptive immunity. They associate with IFN regulatory factor 9 (IRF9) to form a heterotrimeric transcription factor complex known as ISGF3...
Main Authors: | , , |
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Format: | Online |
Language: | English |
Published: |
Landes Bioscience
2013
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3772101/ |