Transcriptional regulation by STAT1 and STAT2 in the interferon JAK-STAT pathway

STAT1 and STAT2 proteins are key mediators of type I and type III interferon (IFN) signaling, and are essential components of the cellular antiviral response and adaptive immunity. They associate with IFN regulatory factor 9 (IRF9) to form a heterotrimeric transcription factor complex known as ISGF3...

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Bibliographic Details
Main Authors: Au-Yeung, Nancy, Mandhana, Roli, Horvath, Curt M
Format: Online
Language:English
Published: Landes Bioscience 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3772101/