Evaluation of urine biomarkers of kidney injury in Polycystic Kidney Disease
Progressive disruption of renal tubular integrity in the setting of increased cellular proliferation and apoptosis is a feature of ADPKD. Here we evaluated the effect of these processes on the expression of NGAL and IL-18, markers of tubular injury, in rodent models and in the cyst fluid and urine o...
Main Authors: | Parikh, Chirag R., Dahl, Neera K., Chapman, Arlene, Bost, James E., Edelstein, Charles L., Comer, Diane M., Zeltner, Raoul, Tian, Xin, Grantham, Jared J., Somlo, Stefan |
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Format: | Online |
Language: | English |
Published: |
2012
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3319327/ |
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