Evaluation of urine biomarkers of kidney injury in Polycystic Kidney Disease

Progressive disruption of renal tubular integrity in the setting of increased cellular proliferation and apoptosis is a feature of ADPKD. Here we evaluated the effect of these processes on the expression of NGAL and IL-18, markers of tubular injury, in rodent models and in the cyst fluid and urine o...

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Bibliographic Details
Main Authors: Parikh, Chirag R., Dahl, Neera K., Chapman, Arlene, Bost, James E., Edelstein, Charles L., Comer, Diane M., Zeltner, Raoul, Tian, Xin, Grantham, Jared J., Somlo, Stefan
Format: Online
Language:English
Published: 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3319327/