BDMC33, A Curcumin Derivative Suppresses Inflammatory Responses in Macrophage-Like Cellular System: Role of Inhibition in NF-κB and MAPK Signaling Pathways

BDMC33, A Curcumin Derivative Suppresses Inflammatory Responses in Macrophage-Like Cellular System: Role of Inhibition in NF-κB and MAPK Signaling Pathways

Our preliminary screening has shown that curcumin derivative BDMC33 [2,6-bis(2,5-dimethoxybenzylidene)cyclohexanone] exerted promising nitric oxide inhibitory activity in activated macrophages. However, the molecular basis and mechanism for its pharmacological action is yet to be elucidated. The aim...

Full description

Bibliographic Details
Main Authors: Lee, Ka-Heng, Chow, Yuh-Lit, Sharmili, Vidyadaran, Abas, Faridah, Alitheen, Noorjahan Banu Mohamed, Shaari, Khozirah, Israf, Daud Ahmad, Lajis, Nordin Haji, Syahida, Ahmad
Format: Online
Language:English
Published: Molecular Diversity Preservation International (MDPI) 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3317699/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3317699/

Similar Items