Characterization of MRFAP1 Turnover and Interactions Downstream of the NEDD8 Pathway*

The NEDD8-Cullin E3 ligase pathway plays an important role in protein homeostasis, in particular the degradation of cell cycle regulators and transcriptional control networks. To characterize NEDD8-cullin target proteins, we performed a quantitative proteomic analysis of cells treated with MLN4924,...

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Bibliographic Details
Main Authors: Larance, Mark, Kirkwood, Kathryn J., Xirodimas, Dimitris P., Lundberg, Emma, Uhlen, Mathias, Lamond, Angus I.
Format: Online
Language:English
Published: The American Society for Biochemistry and Molecular Biology 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3316733/