Characterization of MRFAP1 Turnover and Interactions Downstream of the NEDD8 Pathway*
The NEDD8-Cullin E3 ligase pathway plays an important role in protein homeostasis, in particular the degradation of cell cycle regulators and transcriptional control networks. To characterize NEDD8-cullin target proteins, we performed a quantitative proteomic analysis of cells treated with MLN4924,...
Main Authors: | , , , , , |
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Format: | Online |
Language: | English |
Published: |
The American Society for Biochemistry and Molecular Biology
2012
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3316733/ |