Systematic Analysis of Protein Pools, Isoforms, and Modifications Affecting Turnover and Subcellular Localization*

In higher eukaryotes many genes encode protein isoforms whose properties and biological roles are often poorly characterized. Here we describe systematic approaches for detection of either distinct isoforms, or separate pools of the same isoform, with differential biological properties. Using inform...

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Bibliographic Details
Main Authors: Ahmad, Yasmeen, Boisvert, Francois-Michel, Lundberg, Emma, Uhlen, Mathias, Lamond, Angus I.
Format: Online
Language:English
Published: The American Society for Biochemistry and Molecular Biology 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3316725/