The genetic association between personality and major depression or bipolar disorder. A polygenic score analysis using genome-wide association data

The genetic association between personality and major depression or bipolar disorder. A polygenic score analysis using genome-wide association data

The relationship between major depressive disorder (MDD) and bipolar disorder (BD) remains controversial. Previous research has reported differences and similarities in risk factors for MDD and BD, such as predisposing personality traits. For example, high neuroticism is related to both disorders, w...

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Main Authors: Middeldorp, C M, de Moor, M H M, McGrath, L M, Gordon, S D, Blackwood, D H, Costa, P T, Terracciano, A, Krueger, R F, de Geus, E J C, Nyholt, D R, Tanaka, T, Esko, T, Madden, P A F, Derringer, J, Amin, N, Willemsen, G, Hottenga, J-J, Distel, M A, Uda, M, Sanna, S, Spinhoven, P, Hartman, C A, Ripke, S, Sullivan, P F, Realo, A, Allik, J, Heath, A C, Pergadia, M L, Agrawal, A, Lin, P, Grucza, R A, Widen, E, Cousminer, D L, Eriksson, J G, Palotie, A, Barnett, J H, Lee, P H, Luciano, M, Tenesa, A, Davies, G, Lopez, L M, Hansell, N K, Medland, S E, Ferrucci, L, Schlessinger, D, Montgomery, G W, Wright, M J, Aulchenko, Y S, Janssens, A C J W, Oostra, B A, Metspalu, A, Abecasis, G R, Deary, I J, Räikkönen, K, Bierut, L J, Martin, N G, Wray, N R, van Duijn, C M, Smoller, J W, Penninx, B W J H, Boomsma, D I
Format: Online
Language:English
Published: Nature Publishing Group 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3309491/

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