Effects of IRF5 Lupus Risk Haplotype on Pathways Predicted to Influence B Cell Functions

Effects of IRF5 Lupus Risk Haplotype on Pathways Predicted to Influence B Cell Functions

Both genetic and environmental interactions affect systemic lupus erythematosus (SLE) development and pathogenesis. One known genetic factor associated with lupus is a haplotype of the interferon regulatory factor 5 (IRF5) gene. Analysis of global gene expression microarray data using gene set enric...

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Bibliographic Details
Main Authors: Guthridge, Joel M., Clark, Daniel N., Templeton, Amanda, Dominguez, Nicolas, Lu, Rufei, Vidal, Gabriel S., Kelly, Jennifer A., Kauffman, Kenneth M., Harley, John B., Gaffney, Patrick M., James, Judith A., Poole, Brian D.
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3304673/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3304673/

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