Evidence of Dynamically Dysregulated Gene Expression Pathways in Hyperresponsive B Cells from African American Lupus Patients

by Dozmorov, Igor, Dominguez, Nicolas, Sestak, Andrea L., Robertson, Julie M., Harley, John B., James, Judith A., Guthridge, Joel M.
Published 2013

B-Cell and Monocyte Contribution to Systemic Lupus Erythematosus Identified by Cell-Type-Specific Differential Expression Analysis in RNA-Seq Data

by Dozmorov, Mikhail G., Dominguez, Nicolas, Bean, Krista, Macwana, Susan R., Roberts, Virginia, Glass, Edmund, James, Judith A., Guthridge, Joel M.
Published 2015

Complement C3 Activation Is Required for Antiphospholipid Antibody-induced Fetal Loss

by Holers, V. Michael, Girardi, Guillermina, Mo, Lian, Guthridge, Joel M., Molina, Hector, Pierangeli, Silvia S., Espinola, Ricardo, Xiaowei, Liu E., Mao, Dailing, Vialpando, Christopher G., Salmon, Jane E.
Published 2002

Autoantibody‐Positive Healthy Individuals Display Unique Immune Profiles That May Regulate Autoimmunity

by Slight‐Webb, Samantha, Lu, Rufei, Ritterhouse, Lauren L., Munroe, Melissa E., Maecker, Holden T., Fathman, Charles G., Utz, Paul J., Merrill, Joan T., Guthridge, Joel M., James, Judith A.
Published 2016

Expression and methylation data from SLE patient and healthy control blood samples subdivided with respect to ARID3a levels

by Ward, Julie M., Ratliff, Michelle L., Dozmorov, Mikhail G., Wiley, Graham, Guthridge, Joel M., Gaffney, Patrick M., James, Judith A., Webb, Carol F.
Published 2016

The Effect of Inversion at 8p23 on BLK Association with Lupus in Caucasian Population

by Namjou, Bahram, Ni, Yizhao, Harley, Isaac T. W., Chepelev, Iouri, Cobb, Beth, Kottyan, Leah C., Gaffney, Patrick M., Guthridge, Joel M., Kaufman, Kenneth, Harley, John B.
Published 2014

Internal standard-based analysis of microarray data2—Analysis of functional associations between HVE-genes

by Dozmorov, Igor M., Jarvis, James, Saban, Ricardo, Benbrook, Doris M., Wakeland, Edward, Aksentijevich, Ivona, Ryan, John, Chiorazzi, Nicholas, Guthridge, Joel M., Drewe, Elizabeth, Tighe, Patrick J., Centola, Michael, Lefkovits, Ivan
Published 2011

Effects of IRF5 Lupus Risk Haplotype on Pathways Predicted to Influence B Cell Functions

by Guthridge, Joel M., Clark, Daniel N., Templeton, Amanda, Dominguez, Nicolas, Lu, Rufei, Vidal, Gabriel S., Kelly, Jennifer A., Kauffman, Kenneth M., Harley, John B., Gaffney, Patrick M., James, Judith A., Poole, Brian D.
Published 2012

Vitamin D Deficiency in a Multiethnic Healthy Control Cohort and Altered Immune Response in Vitamin D Deficient European-American Healthy Controls

by Ritterhouse, Lauren L., Lu, Rufei, Shah, Hemangi B., Robertson, Julie M., Fife, Dustin A., Maecker, Holden T., Du, Hongwu, Fathman, Charles G., Chakravarty, Eliza F., Scofield, R. Hal, Kamen, Diane L., Guthridge, Joel M., James, Judith A.
Published 2014

Multiple Autoantibodies Display Association with Lymphopenia, Proteinuria, and Cellular Casts in a Large, Ethnically Diverse SLE Patient Cohort

by Lu, Rufei, Robertson, Julie M., Bruner, Benjamin F., Guthridge, Joel M., Neas, Barbara R., Nath, Swapan K., Kelly, Jennifer A., Moser Sivils, Kathy L., Chakravarty, Eliza F., Kamen, Diane L., Gilkeson, Gary S., Wallace, Daniel J., Weisman, Michael H., Scofield, R. Hal, Harley, John B., James, Judith A.
Published 2012

Trans-Ancestral Studies Fine Map the SLE-Susceptibility Locus TNFSF4

by Manku, Harinder, Langefeld, Carl D., Guerra, Sandra G., Malik, Talat H., Alarcon-Riquelme, Marta, Anaya, Juan-Manuel, Bae, Sang-Cheol, Boackle, Susan A., Brown, Elizabeth E., Criswell, Lindsey A., Freedman, Barry I., Gaffney, Patrick M., Gregersen, Peter A., Guthridge, Joel M., Han, Sang-Hoon, Harley, John B., Jacob, Chaim O., James, Judith A., Kamen, Diane L., Kaufman, Kenneth M., Kelly, Jennifer A., Martin, Javier, Merrill, Joan T., Moser, Kathy L., Niewold, Timothy B., Park, So-Yeon, Pons-Estel, Bernardo A., Sawalha, Amr H., Scofield, R. Hal, Shen, Nan, Stevens, Anne M., Sun, Celi, Gilkeson, Gary S., Edberg, Jeff C., Kimberly, Robert P., Nath, Swapan K., Tsao, Betty P., Vyse, Tim J.
Published 2013

PTPN22 Association in Systemic Lupus Erythematosus (SLE) with Respect to Individual Ancestry and Clinical Sub-Phenotypes

by Namjou, Bahram, Kim-Howard, Xana, Sun, Celi, Adler, Adam, Chung, Sharon A., Kaufman, Kenneth M., Kelly, Jennifer A., Glenn, Stuart B., Guthridge, Joel M., Scofield, Robert H., Kimberly, Robert P., Brown, Elizabeth E., Alarcón, Graciela S., Edberg, Jeffrey C., Kim, Jae-Hoon, Choi, Jiyoung, Ramsey-Goldman, Rosalind, Petri, Michelle A., Reveille, John D., Vilá, Luis M., Boackle, Susan A., Freedman, Barry I., Tsao, Betty P., Langefeld, Carl D., Vyse, Timothy J., Jacob, Chaim O., Pons-Estel, Bernardo, Niewold, Timothy B., Moser Sivils, Kathy L., Merrill, Joan T., Anaya, Juan-Manuel, Gilkeson, Gary S., Gaffney, Patrick M., Bae, Sang-Cheol, Alarcón-Riquelme, Marta E., Harley, John B., Criswell, Lindsey A., James, Judith A., Nath, Swapan K.
Published 2013

Admixture Mapping in Lupus Identifies Multiple Functional Variants within IFIH1 Associated with Apoptosis, Inflammation, and Autoantibody Production

by Molineros, Julio E., Maiti, Amit K., Sun, Celi, Looger, Loren L., Han, Shizhong, Kim-Howard, Xana, Glenn, Stuart, Adler, Adam, Kelly, Jennifer A., Niewold, Timothy B., Gilkeson, Gary S., Brown, Elizabeth E., Alarcón, Graciela S., Edberg, Jeffrey C., Petri, Michelle, Ramsey-Goldman, Rosalind, Reveille, John D., Vilá, Luis M., Freedman, Barry I., Tsao, Betty P., Criswell, Lindsey A., Jacob, Chaim O., Moore, Jason H., Vyse, Timothy J., Langefeld, Carl L., Guthridge, Joel M., Gaffney, Patrick M., Moser, Kathy L., Scofield, R. Hal, Alarcón-Riquelme, Marta E., Williams, Scott M., Merrill, Joan T., James, Judith A., Kaufman, Kenneth M., Kimberly, Robert P., Harley, John B., Nath, Swapan K.
Published 2013

Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis

by Hinks, Anne, Cobb, Joanna, Marion, Miranda C., Prahalad, Sampath, Sudman, Marc, Bowes, John, Martin, Paul, Comeau, Mary E., Sajuthi, Satria, Andrews, Robert, Brown, Milton, Chen, Wei-Min, Concannon, Patrick, Deloukas, Panos, Edkins, Sarah, Eyre, Stephen, Gaffney, Patrick M., Guthery, Stephen L., Guthridge, Joel M., Hunt, Sarah E., James, Judith A., Keddache, Mehdi, Moser, Kathy L., Nigrovic, Peter A., Onengut-Gumuscu, Suna, Onslow, Mitchell L., Rosé, Carlos D., Rich, Stephen S., Steel, Kathryn J.A., Wakeland, Edward K., Wallace, Carol A., Wedderburn, Lucy R., Woo, Patricia, Bohnsack, John F., Haas, Johannes Peter, Glass, David N., Langefeld, Carl D., Thomson, Wendy, Thompson, Susan D.
Published 2013

Association of Genetic Variants in Complement Factor H and Factor H-Related Genes with Systemic Lupus Erythematosus Susceptibility

by Zhao, Jian, Wu, Hui, Khosravi, Melanie, Cui, Huijuan, Qian, Xiaoxia, Kelly, Jennifer A., Kaufman, Kenneth M., Langefeld, Carl D., Williams, Adrienne H., Comeau, Mary E., Ziegler, Julie T., Marion, Miranda C., Adler, Adam, Glenn, Stuart B., Alarcón-Riquelme, Marta E., Pons-Estel, Bernardo A., Harley, John B., Bae, Sang-Cheol, Bang, So-Young, Cho, Soo-Kyung, Jacob, Chaim O., Vyse, Timothy J., Niewold, Timothy B., Gaffney, Patrick M., Moser, Kathy L., Kimberly, Robert P., Edberg, Jeffrey C., Brown, Elizabeth E., Alarcon, Graciela S., Petri, Michelle A., Ramsey-Goldman, Rosalind, Vilá, Luis M., Reveille, John D., James, Judith A., Gilkeson, Gary S., Kamen, Diane L., Freedman, Barry I., Anaya, Juan-Manuel, Merrill, Joan T., Criswell, Lindsey A., Scofield, R. Hal, Stevens, Anne M., Guthridge, Joel M., Chang, Deh-Ming, Song, Yeong Wook, Park, Ji Ah, Lee, Eun Young, Boackle, Susan A., Grossman, Jennifer M., Hahn, Bevra H., Goodship, Timothy H. J., Cantor, Rita M., Yu, Chack-Yung, Shen, Nan, Tsao, Betty P.
Published 2011

Variants at multiple loci implicated in both innate and adaptive immune responses are associated with Sjögren’s syndrome

by Lessard, Christopher J., Li, He, Adrianto, Indra, Ice, John A., Rasmussen, Astrid, Grundahl, Kiely M., Kelly, Jennifer A., Dozmorov, Mikhail G., Miceli-Richard, Corinne, Bowman, Simon, Lester, Sue, Eriksson, Per, Eloranta, Maija-Leena, Brun, Johan G., Gøransson, Lasse G., Harboe, Erna, Guthridge, Joel M., Kaufman, Kenneth M., Kvarnström, Marika, Jazebi, Helmi, Graham, Deborah S. Cunninghame, Grandits, Martha E., Nazmul-Hossain, Abu N. M., Patel, Ketan, Adler, Adam J., Maier-Moore, Jacen S., Farris, A. Darise, Brennan, Michael T., Lessard, James A., Chodosh, James, Gopalakrishnan, Rajaram, Hefner, Kimberly S., Houston, Glen D., Huang, Andrew J.W., Hughes, Pamela J., Lewis, David M., Radfar, Lida, Rohrer, Michael D., Stone, Donald U., Wren, Jonathan D., Vyse, Timothy J., Gaffney, Patrick M., James, Judith A., Omdal, Roald, Wahren-Herlenius, Marie, Illei, Gabor G., Witte, Torsten, Jonsson, Roland, Rischmueller, Maureen, Rönnblom, Lars, Nordmark, Gunnel, Ng, Wan-Fai, Mariette, Xavier, Anaya, Juan-Manuel, Rhodus, Nelson L., Segal, Barbara M., Scofield, R. Hal, Montgomery, Courtney G., Harley, John B., Sivils, Kathy L. Moser
Published 2013

Preferential association of a functional variant in complement receptor 2 with antibodies to double-stranded DNA

by Zhao, Jian, Giles, Brendan M, Taylor, Rhonda L, Yette, Gabriel A, Lough, Kara M, Ng, Han Leng, Abraham, Lawrence J, Wu, Hui, Kelly, Jennifer A, Glenn, Stuart B, Adler, Adam J, Williams, Adrienne H, Comeau, Mary E, Ziegler, Julie T, Marion, Miranda, Alarcón-Riquelme, Marta E, Alarcón, Graciela S, Anaya, Juan-Manuel, Bae, Sang-Cheol, Kim, Dam, Lee, Hye-Soon, Criswell, Lindsey A, Freedman, Barry I, Gilkeson, Gary S, Guthridge, Joel M, Jacob, Chaim O, James, Judith A, Kamen, Diane L, Merrill, Joan T, Sivils, Kathy Moser, Niewold, Timothy B, Petri, Michelle A, Ramsey-Goldman, Rosalind, Reveille, John D, Scofield, R Hal, Stevens, Anne M, Vilá, Luis M, Vyse, Timothy J, Kaufman, Kenneth M, Harley, John B, Langefeld, Carl D, Gaffney, Patrick M, Brown, Elizabeth E, Edberg, Jeffrey C, Kimberly, Robert P, Ulgiati, Daniela, Tsao, Betty P, Boackle, Susan A
Published 2016

Lupus risk variants in the PXK locus alter B-cell receptor internalization

by Vaughn, Samuel E., Foley, Corinne, Lu, Xiaoming, Patel, Zubin H., Zoller, Erin E., Magnusen, Albert F., Williams, Adrienne H., Ziegler, Julie T., Comeau, Mary E., Marion, Miranda C., Glenn, Stuart B., Adler, Adam, Shen, Nan, Nath, Swapan, Stevens, Anne M., Freedman, Barry I., Tsao, Betty P., Jacob, Chaim O., Kamen, Diane L., Brown, Elizabeth E., Gilkeson, Gary S., Alarcón, Graciela S., Reveille, John D., Anaya, Juan-Manuel, James, Judith A., Moser, Kathy L., Criswell, Lindsey A., Vilá, Luis M., Alarcón-Riquelme, Marta E., Petri, Michelle, Scofield, R. Hal, Kimberly, Robert P., Ramsey-Goldman, Rosalind, Binjoo, Young, Choi, Jeongim, Bae, Sang-Cheol, Boackle, Susan A., Vyse, Timothy J., Guthridge, Joel M., Namjou, Bahram, Gaffney, Patrick M., Langefeld, Carl D., Kaufman, Kenneth M., Kelly, Jennifer A., Harley, Isaac T. W., Harley, John B., Kottyan, Leah C.
Published 2015