PHACTS, a computational approach to classifying the lifestyle of phages
Motivation: Bacteriophages have two distinct lifestyles: virulent and temperate. The virulent lifestyle has many implications for phage therapy, genomics and microbiology. Determining which lifestyle a newly sequenced phage falls into is currently determined using standard culturing techniques. Such...
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| Format: | Online |
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Oxford University Press
2012
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3289917/ |
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pubmed-32899172012-02-29 PHACTS, a computational approach to classifying the lifestyle of phages McNair, Katelyn Bailey, Barbara A. Edwards, Robert A. Original Papers Motivation: Bacteriophages have two distinct lifestyles: virulent and temperate. The virulent lifestyle has many implications for phage therapy, genomics and microbiology. Determining which lifestyle a newly sequenced phage falls into is currently determined using standard culturing techniques. Such laboratory work is not only costly and time consuming, but also cannot be used on phage genomes constructed from environmental sequencing. Therefore, a computational method that utilizes the sequence data of phage genomes is needed. Oxford University Press 2012-03-01 2012-01-11 /pmc/articles/PMC3289917/ /pubmed/22238260 http://dx.doi.org/10.1093/bioinformatics/bts014 Text en © The Author(s) 2012. Published by Oxford University Press. http://creativecommons.org/licenses/by-nc/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| repository_type |
Open Access Journal |
| institution_category |
Foreign Institution |
| institution |
US National Center for Biotechnology Information |
| building |
NCBI PubMed |
| collection |
Online Access |
| language |
English |
| format |
Online |
| author |
McNair, Katelyn Bailey, Barbara A. Edwards, Robert A. |
| spellingShingle |
McNair, Katelyn Bailey, Barbara A. Edwards, Robert A. PHACTS, a computational approach to classifying the lifestyle of phages |
| author_facet |
McNair, Katelyn Bailey, Barbara A. Edwards, Robert A. |
| author_sort |
McNair, Katelyn |
| title |
PHACTS, a computational approach to classifying the lifestyle of phages |
| title_short |
PHACTS, a computational approach to classifying the lifestyle of phages |
| title_full |
PHACTS, a computational approach to classifying the lifestyle of phages |
| title_fullStr |
PHACTS, a computational approach to classifying the lifestyle of phages |
| title_full_unstemmed |
PHACTS, a computational approach to classifying the lifestyle of phages |
| title_sort |
phacts, a computational approach to classifying the lifestyle of phages |
| description |
Motivation: Bacteriophages have two distinct lifestyles: virulent and temperate. The virulent lifestyle has many implications for phage therapy, genomics and microbiology. Determining which lifestyle a newly sequenced phage falls into is currently determined using standard culturing techniques. Such laboratory work is not only costly and time consuming, but also cannot be used on phage genomes constructed from environmental sequencing. Therefore, a computational method that utilizes the sequence data of phage genomes is needed. |
| publisher |
Oxford University Press |
| publishDate |
2012 |
| url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3289917/ |
| _version_ |
1611509158316605440 |