Interferon gamma (IFN-γ) disrupts energy expenditure and metabolic homeostasis by suppressing SIRT1 transcription
Chronic inflammation impairs metabolic homeostasis and is intimately correlated with the pathogenesis of type 2 diabetes. The pro-inflammatory cytokine IFN-γ is an integral part of the metabolic inflammation circuit and contributes significantly to metabolic dysfunction. The underlying mechanism, ho...
Main Authors: | , , , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
Oxford University Press
2012
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287208/ |